发明名称 9-DEAZAHYPOXANTHINES AS PNP INHIBITORS
摘要 Compounds of formula (I) wherein R1 is C5-9 cycloalkyl, phenyl optionally substituted by one or two moieties selected from the group consisting of halogen, C1-C3-alkyl, C1-C3-alkoxy, benzyloxy, hydroxy, and trifluoromethyl, 2- or 3-thienyl, 2- or 3-furanyl, 2-, 3-, or 4-pyridyl, or a salt or hydrate thereof, are useful as purine nucleoside phosphorylase (PNP) inhibitors.
申请公布号 WO9501355(A1) 申请公布日期 1995.01.12
申请号 WO1994IB00165 申请日期 1994.06.20
申请人 BIOCRYST PHARMACEUTICALS, INC. 发明人 MONTGOMERY, JOHN, A.;NIWAS, SHRI
分类号 C07D487/04;(IPC1-7):C07D487/04;A61K31/505 主分类号 C07D487/04
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