| 摘要 |
NEW MATERIAL:A compound expressed by formula I or II (X is alkyl, halogen or nitro; Y is alkyl, halogen, nitro, amino, OH or carboxy; R is alkyl; m and n are 0-2). USE:An agricultural or horticultural germicide or intermediate therefor. PREPARATION:The nuclear nitrogen atom of isoquinoline is alkylated with an alkylating agent, e.g. alkyl halide, etc., to give an N-alkylisoquinolinium salt, which is then reacted with indole in the presence of an alkali to provide a compound expressed by formula II. The resultant compound expressed by formula II is then hydrogenated with sodium borohydride, catalytically hydrogenated in the presence of a platinum catalyst, etc., to afford the aimed compound expressed by formula I. |
