发明名称 Quinoxaline biphenyl angiotensin II inhibitors
摘要 Angiotensin II inhibition is exhibited by <IMAGE> wherein: X is -CH2- or O; R is hydrogen, alkyl, aryl, cycloalkyl, aralkyl, or cycloalkylalkyl; R1 and R2 are each independently O or absent; R3 is hydrogen, alkyl, alkenyl, alkoxy, cycloalkyl, aryl, aralkyl, cycloalkylalkyl, halo, haloalkyl, or haloalkoxy; R4 is hydrogen, alkyl, alkenyl, alkoxy, aryl, cycloalkyl, aralkyl, cycloalkylalkyl, -R8-OH, or -R8CO2R9; and the remaining symbols are as defined in the specification.
申请公布号 US5380719(A) 申请公布日期 1995.01.10
申请号 US19920876729 申请日期 1992.04.28
申请人 E. R. SQUIBB & SONS, INC. 发明人 KIM, KYOUNG S.
分类号 C07D403/10;C07D403/12;C07F9/6509;(IPC1-7):A61K31/675;A61K31/495 主分类号 C07D403/10
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