| 摘要 |
This invention encompasses compounds of the following formula and the stereoisomers and pharmaceutically acceptable salts thereof. <IMAGE> I wherein R represents lower alkyl of 1 to 6 carbon atoms, lower alkenyl of 2 to 6 carbon atoms, or -(CH2)m-R3 wherein R3 represents cycloalkyl of 3 to 5 carbon atoms and m is 1, 2 or 3; R1 is -CONH2 or <IMAGE> NHSO2R2 wherein R2 is lower alkyl, phenyl, unsubstituted or substituted with loweralkyl, orcompounds are useful anti-inflammatory agents for treating, for example, inflammatory bowel disease, rheumatoid arthritis, gout, asthma and psoriasis.
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