| 摘要 |
Disclosed are DNA and other biological compositions, including biological cultures, for preparing Haemophilus influenzae antigens by recombinant means. The disclosed recombinant antigens are suitable for use in the preparation of immunogenic compositions for use in vaccination against various Haemophilus influenzae type B infections. Particular embodiments disclosed include DNA segments which encode the P2 major outer membrane protein antigen, also referred to as the 39/38 protein, biological cultures transformed by these DNA segments, and the preparation of recombinant P2 antigen through the use of these biological cultures.
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