| 摘要 |
PURPOSE:To provide the subject agent and substance suppressing the proliferation of Streptococcus in the oral cavity, free from risks of side effects, thus useful in troches or toothpaste for preventing or curing dental caries, containing, as active ingredient, Sophora exigua extract. CONSTITUTION:The objective agent/substance containing, as active ingredient, 5,7,2',6'-tetrahydroxy-8-lavandulyl flavanone of formula I or 5,7,2',4'- tetrahydroxy-8-lavandulyl flavanone of formula II which can be obtained by extracting Sophora exigua (pref. its roots), a kind of leguminous plant, with a solvent such as water, MeOH, EtOH or acetone, either singly or in the form of a combination thereof, or repeatedly. |
