发明名称 |
METHOD OF PRODUCING SUSTAINED-RELEASE PREPARATION |
摘要 |
A method of producing a sustained-release preparation which includes permitting a water-soluble polypeptide to permeate into a biodegradable matrix in the aqueous solution. The production method of the present invention makes possible the permeation of a water-soluble polypeptide into a biodegradable matrix without bringing the water-soluble polypeptide into contact with an organic solvent. Hence the water-soluble polypeptide is prepared without affecting the water-soluble polypeptide bioactivity and is thus effective for use as a pharmaceutical.
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申请公布号 |
CA2127317(A1) |
申请公布日期 |
1995.01.06 |
申请号 |
CA19942127317 |
申请日期 |
1994.07.04 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD. |
发明人 |
IGARI, YASUTAKA;YAMAMOTO, KAZUMICHI;OKAMOTO, KAYOKO;YAMAGATA, YUTAKA |
分类号 |
A61K9/16;A61K9/52;(IPC1-7):A61K38/19;A61K9/14;A61K47/34;A61K9/50 |
主分类号 |
A61K9/16 |
代理机构 |
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地址 |
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