发明名称 |
BIOLOGICALLY ACTIVE VASOPRESSIN ANALOGUES |
摘要 |
Vasopressin analogues of formula (I) wherein X is (S)-2-amino-2-methyl-butanoic acid (C.alpha.MeAbu) or Valine (Val), Y is Thienylalanine (THi) or Methionine (Met), Z is D-Phenylalanine (D-Phe) or D-Thienylalanine (Thi) or DTyrosine (D-Tyr), are disclosed. Pharmaceutical preparations comprising a vasopressin analogue of the invention as active ingredient are disclosed and a exemplified by oral preparations, nasal preparations, and intravenous preparations. The vasopressin analogues of the invention are intended for use as a medicament, specially an antidiuretic agent. The antidiuretic agent is preferably used for the treatment of diabetes insipidus or enuresis.
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申请公布号 |
CA2163352(A1) |
申请公布日期 |
1995.01.05 |
申请号 |
CA19942163352 |
申请日期 |
1994.06.16 |
申请人 |
FERRING B.V. |
发明人 |
NILSSON, ANDERS;OLSSON, H KAN;SOEDERBERG-AHLM, CHRISTINA;TROJNAR, JERZY |
分类号 |
A61K38/11;A61K38/00;A61P13/02;A61P15/00;C07K7/16;(IPC1-7):C07K7/16;A61K38/08 |
主分类号 |
A61K38/11 |
代理机构 |
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主权项 |
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