发明名称 |
BIOLOGICALLY ACTIVE VASOPRESSIN ANALOGUES |
摘要 |
Vasopressin analogues of formula (I) wherein X is (S)-2-amino-2-methyl-butanoic acid (C alpha MeAbu) or Valine (Val), Y is Thienylalanine (Thi) or Methionine (Met), Z is D-Phenylalanine (D-Phe) or D-Thienylalanine (Thi) or D-Tyrosine (D-Tyr), are disclosed. Pharmaceutical preparations comprising a vasopressin analogue of the invention as active ingredient are disclosed and exemplified by oral preparations, nasal preparations, and intravenous preparations. The vasopressin analogues of the invention are intended for use as a medicament, specially an antidiuretic agent. The antidiuretic agent is preferably used for the treatment of diabetes insipidus or enuresis.
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申请公布号 |
WO9500548(A1) |
申请公布日期 |
1995.01.05 |
申请号 |
WO1994SE00594 |
申请日期 |
1994.06.16 |
申请人 |
FERRING B.V.;NILSSON, ANDERS;OLSSON, HAAKAN;SOEDERBERG-AHLM, CHRISTINA;TROJNAR, JERZY |
发明人 |
NILSSON, ANDERS;OLSSON, HAAKAN;SOEDERBERG-AHLM, CHRISTINA;TROJNAR, JERZY |
分类号 |
A61K38/11;A61K38/00;A61P13/02;A61P15/00;C07K7/16;(IPC1-7):C07K7/16;A61K37/34 |
主分类号 |
A61K38/11 |
代理机构 |
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