发明名称 |
Tricyclic compounds |
摘要 |
A tricyclic compound represented by the following formula (I): <IMAGE> (I) wherein R1 represents hydrogen, halogen or lower alkyl; A represents cyano, carboxyl, tetrazolyl, cyano-substituted phenyl, carboxyl-substituted phenyl or tetrazolyl-substituted phenyl; V represents -(CH2)m- wherein m is an integer of 0 to 2; W represents <IMAGE> and Q1-Q2-Q3-Q4 represents N=CH-CH=CH, CH=CH-CH=CH or CH2-CH2-CH2-CH2, <IMAGE> <IMAGE> <IMAGE> and Q represents N or CH; X1-X2-X3 represents CH=CH-CH=CH, S-CH=CH or CH=CH-S; Y represents CH2CH2; and Z1-Z2 represents N-(CH2)n- wherein n is an integer of 1 to 3 or a pharmaceutically acceptable salt thereof.
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申请公布号 |
US5378701(A) |
申请公布日期 |
1995.01.03 |
申请号 |
US19930065916 |
申请日期 |
1993.05.25 |
申请人 |
KYOWA HAKKO KOGYO |
发明人 |
OHSHIMA, ETSUO;KANAI, FUMIHIKO;SATO, HIDEYUKI;OBASE, HIROYUKI;KUMAZAWA, TOSHIAKI;TAKAHARA, SHIHO;OHNO, TETSUJI;ISHIKAWA, TOMOKO;YAMADA, KOJI |
分类号 |
C07D403/06;C07D403/12;C07D403/14;C07D405/06;C07D471/04;C07D521/00;(IPC1-7):A61K31/55;C07D223/16;C07D223/22 |
主分类号 |
C07D403/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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