| 摘要 |
Unimolecular micelles, generally referred to as cascade polymers, are constructed via the addition of successive layers, or tiers, of designed monomers, or building blocks, that possess a predetermined, branched superstructure consisting of connected physical matter inherently defining an internal void volume or void area within the molecular framework. Reactive sites located on the framework and hence within the void regions are capable of being chemically transformed to allow covalent and noncovalent incorporation of one or more guest species into the said void regions. Further, a method is described for making such cascade polymers that includes the steps of forming a unimolecular micelle containing internal void areas with accessible reactive sites capable of bonding to at least one guest after construction of the said unimolecular micelle. The guests are contained within the internal void volume of the cascade polymer and are available and accessible for additional chemical modification.
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