摘要 |
<p>The present invention provides a compound having the formula (II) wherein R2 is a hydrogen atom or an amino-protecting group selected from a tri-alkylsilyl group, an acyl group, a chloroacetyl group, a p-methoxybenzyloxycarbonyl group, a tbutoxycarbonyl group, a 2,2,2-trichloroethoxycarbonyl group, a pnitrobenzyloxycarbonyl group, an aralkyl group, a p-methoxybenzyl group, a p-nitrobenzyl group, a benzhydryl group and a trityl group, and each of R3 and R4 is a hydrogen atom or a hydroxylprotecting group, trialkylsily group, a benzhydryl group, a .beta. methylsulfonylethyl group, a phenacyl group, a p-methoxybenzyl group, a t-butyl group, a p-nitrobenzyl group, and a 2,2,2trichloroethyl group or a reactive derivative thereof selected from a salt, halide, ester, anhydride, amide, azide which compounds are intermediates in the preparation of cephalosporin antibacterial compounds.</p> |
申请人 |
KAKEN PHARMACEUTICAL CO., LTD. |
发明人 |
ZAMA, YOSHIYUKI;ISHIYAMA, NOBUO;SAITA, TSUNEO;NAITO, TAKANOBU;HIROSE, MASAO;YOKOYAMA, MASAAKI;ASANO, TAIJI;SENDA, HISATO;SEKINE, KEIJI;SANAI, SHIGERU |