| 发明名称 |
5,10-methylene-tetrahydrofolate as a modulator of a chemotherapeutic agent |
| 摘要 |
The present invention relates to the compound 5,10-methylene-tetrahydrofolate (CH2FH4), and its solution product isomer FH4, therapeutic uses of these compounds, and compositions thereof. CH2FH4 and FH4 strongly modulate the in vivo antitumor effects of 5-Fluorouracil.
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| 申请公布号 |
US5376658(A) |
申请公布日期 |
1994.12.27 |
| 申请号 |
US19930174571 |
申请日期 |
1993.12.23 |
| 申请人 |
UNIVERSITY OF SOUTHERN CALIFORNIA |
发明人 |
SPEARS, COLIN P.;GUSTAVSSON, BENGT G. |
| 分类号 |
A61K31/505;(IPC1-7):A61K31/505;A61K49/00 |
主分类号 |
A61K31/505 |
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