Methods To Prepare Carbon-Isotope Labeled Organohalides With High Specific Radioactivity From Carbon-Isotope Monoxide

摘要

Methods and reagents for labeling synthesis of organohalides by transition metal mediated carbonylation reactions using carbon-isotope labeled carbon monoxide are provided. The resultant carbon-isotope labeled organohalides are useful as radiopharmaceuticals, especially for use as precursors in Positron Emission Tomography (PET). Associated PET tracers and kits for PET studies are also provided.