A novel class of compounds, known as peptide nucleic acids, bind complementary ssDNA and RNA strands more strongly than a corresponding DNA. The peptide nucleic acids generally comprise ligands such as naturally occurring DNA bases attached to a peptide backbone through a suitable linker.
申请公布号
WO9425477(A3)
申请公布日期
1994.12.22
申请号
WO1994IB00142
申请日期
1994.04.25
申请人
NIELSEN, PETER, E.;BUCHARDT, OLE;EGHOLM, MICHAEL;BERG, ROLF, H.
发明人
NIELSEN, PETER, E.;BUCHARDT, OLE;EGHOLM, MICHAEL;BERG, ROLF, H.