发明名称 N-[[1-[4-(4-FLUOROPHENOXY)BUTYL] -4-PIPERIDINYL]-N-METHYLAMINO]-2-BENZOTHIAZOLOLS AS CLASS III ANTIARRHYTHMIC AGENTS
摘要 2-¢¢1-¢4-(4-fluorophenoxy)butyl!-4-piperidinyl!methylamino!-benzothiazololes of formula (I), wherein R1 or R2 is hydroxy, the other variable always being hydrogen, and the pharmaceutically acceptable acid addition salts thereof. Novel compounds, pharmaceutical compositions, as well as their use as a class III antiarrhythmicum is disclosed.
申请公布号 CA2163018(A1) 申请公布日期 1994.12.22
申请号 CA19942163018 申请日期 1994.06.06
申请人 JANSSEN PHARMACEUTICA N.V. 发明人 WILHELM, DORIS;BORDERS MARCEL JAN MARIA;WILHELM DORIS
分类号 C07D277/12;A61K31/425;A61K31/428;A61K31/445;A61K31/454;A61P9/06;C07D417/12;(IPC1-7):C07D417/12 主分类号 C07D277/12
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