发明名称 |
Preparation of chiral amino-nitriles |
摘要 |
A process and intermediates for producing 3-amino nitrites. The process involves resolving an enantiomeric mixture of chiral 3-amino nitrites in the presence of a chiral acid in a solvent system to produce a chiral 3-amino nitrile salt. The process may further comprise a recrystalizing step, wherein an enantiomerically enriched 3-amino nitrile salt is produced. The process may further comprise a salt exchanging step, wherein another acid is added to the chiral 3-amino nitrile salt or the enantiomerically enriched 3-amino nitrile salt to produce another 3-amino nitrile salt.
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申请公布号 |
US7301044(B2) |
申请公布日期 |
2007.11.27 |
申请号 |
US20040946167 |
申请日期 |
2004.09.21 |
申请人 |
PFIZER INC. |
发明人 |
ALLEN DAVID ROBERT;ACHENBACH-MCCARTHY CRYSTAL A |
分类号 |
C07C253/34;C07C255/03;C07B57/00;C07C69/78;C07C253/30;C07C255/24 |
主分类号 |
C07C253/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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