| 摘要 |
<p>An 8-(2-aminoalkoxy)fluorochroman derivative represented by general formula (I) or a salt thereof, both having a selective affinity for 5-HT1A receptors and being useful for treating psychoneurotic diseases such as anxiety, manic-depressive state and schizophrenia, sex disorder, eating disorder, sleep disorder, and drug dependence: wherein R1, R2 and R3 represent each lower alkoxy, etc., or R1 and R2 may be combined together to represent -O-(CH2)m-O- (wherein m is an integer of 1 to 3), etc.; R4 represents hydrogen, lower alkyl or aralkyl; R5 represent hydroxy, amino or lower alkoxy; R6 represents hydrogen or lower alkyl, provided R5, R6 and the carbon atom to which they are bonded are combined together to represent carbonyl; A represents an ethylene group which may be substituted by lower alkyl; and B represents optionally branched C1-C10 alkylene.</p> |
