Enzymatic preparation of chiral epoxide or hydroxy compounds by stereoselective epoxidation or hydroxylation.

摘要

An enzymatic process for the preparation of chiral epoxides, monohydroxy or dihydroxy compounds of formula <CHEM> by the stereoselective epoxidation or hydroxylation of benzopyrans of formula <CHEM> or resolution of compounds of formula <CHEM> The compounds of formula I and II are intermediates useful in the preparation of pyranyl cyanoguanidine derivatives.