Piperidine derivatives, their preparation and use

摘要

Piperidine derivatives of formula wherein A is straight or branched alkyl, alkoxy-alkyl, or alkenyl; X is O or NH; Y is O, S, NH, NCN, or N-alkyl; R1 is 6-fluoro-1,2-benzisoxazol-3-yl, 6-fluoro-1H-indazol-3-yl, or 6-fluoro-1-methyl-1H-indazol-3-yl; R2 is alkyl or phenyl; and R3 is phenyl optionally substituted, or R3 is wherein Z represents a 5- or 6-membered heterocyclic ring; or R2 and R3 together with the nitrogen atom form a fused heterocyclic ring system; or pharmaceutically acceptable salts thereof are useful in the treatment of indications related to the CNS-system, cardiovascular system or to gastrointestinal disorders.