发明名称 |
Amino acid derivatives with renin-inhibiting properties, a process for the preparation thereof, agents containing these, and the use thereof |
摘要 |
Amino acid derivatives with renin-inhibiting properties, a process for the preparation thereof, agents containing these, and the use thereof The invention relates to renin-inhibiting amino acid derivatives of the formula <IMAGE> in which R1 is a radical of a substituted nitrogen-containing heterocycle such as piperidine, X is CO, CS, SO2 or SO, Y is CH2, O or S, B is the radical of an amino acid of the formula H-B-OH, and R3, R4 and R5 are as defined in the description, a process for the preparation thereof, agents containing these, and the use thereof.
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申请公布号 |
US5374731(A) |
申请公布日期 |
1994.12.20 |
申请号 |
US19900579695 |
申请日期 |
1990.09.10 |
申请人 |
HOECHST AKTIENGESELLSCHAFT |
发明人 |
HEITSCH, HOLGER;HENNING, RAINER;LINZ, WOLFGANG;NICKEL, WOLF-ULRICH;RUPPERT, DIETER;URBACH, HANSJOERG |
分类号 |
A61K31/44;A61K31/4427;A61K31/443;A61K31/4433;A61K31/445;A61P9/12;C07D401/12;C07D401/14;C07D405/14;C07D409/14;C07D417/14;C07K5/02;(IPC1-7):C07D401/12;A61K31/455 |
主分类号 |
A61K31/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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