| 发明名称 |
Modified factor vii |
| 摘要 |
The catalytic active site of Factor VII is modified to produce a compound which effectively interrupts the blood coagulation cascade. The modification render Factor VIIa substantially unable to activate plasma Factors X or IX. Pharmaceutical compositions of the modified Factor VII are used to treat a variety of coagulation-related disorders. |
| 申请公布号 |
AU6956094(A) |
申请公布日期 |
1994.12.20 |
| 申请号 |
AU19940069560 |
申请日期 |
1994.05.23 |
| 申请人 |
ZYMOGENETICS, INC.;NOVO-NORDISCH A/S |
发明人 |
KATHLEEN L. BERKNER;LARS CHRISTIAN PETERSEN;CHARLES E. HART |
| 分类号 |
A61K38/43;A61K38/00;A61K38/55;A61P7/02;A61P9/08;C12N9/64 |
主分类号 |
A61K38/43 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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