COMPUESTOS DERIVADOS DE HETEROARIL-CARBOXAMIDA, ANTAGONISTAS DEL RECEPTOR DE QUIMIOQUINA; COMPOSICION FARMACEUTICA; Y USO PARA EL TRATAMIENTO O PREVENCION DE ENFERMEDADES TALES COMO RECHAZO DE TRANSPLANTE DE ORGANOS, ARTRITIS REUMATOIDEA, LUPUS, ENTR

摘要

Chemokine receptor antagonists, in particular, compounds of Formula (I) that act as antagonists of the chemokine CCR2 receptor, including pharmaceutical compositions and uses thereof to treat or prevent diseases associated with monocyte accumulation, lymphocyte accumulation or leukocyte accumulation are described herein.