发明名称 Ampa antagonists and a method of treatment therewith
摘要 The present patent application discloses compounds having formula (I) or a pharmaceutically acceptable salt thereof wherein R<1> is hydrogen, alkyl or benzyl; X is O or NOR<2>, wherein R<2> is hydrogen, alkyl or benzyl; Y is N-R<4> wherein R<4> is hydrogen, OH or alkyl; n is 0 or 1; R<6> is phenyl, naphthyl, thienyl, pyridyl, all of which may be substituted one or more times with substituents selected from the group consisting of halogen; CF3, NO2, amino, alkyl, alkoxy and phenyl; A is a ring of five to seven atoms fused with the benzo ring at the positions marked a and b. The compounds are useful in the treatment of cerebrovascular disorders for example.
申请公布号 AU6926494(A) 申请公布日期 1994.12.12
申请号 AU19940069264 申请日期 1994.05.09
申请人 NEUROSEARCH A/S 发明人 FRANK WATJEN;JAERGEN DREJER
分类号 C07D241/44;A61K31/495;A61P9/00;A61P25/00;A61P25/04;A61P25/08;A61P25/18;A61P25/22;A61P25/28;A61P25/30;A61P43/00;C07D471/04;C07D487/04;C07D498/04 主分类号 C07D241/44
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