发明名称 |
VITAMIN D COMPOUNDS AND METHOD OF PREPARING THESE COMPOUNDS |
摘要 |
The invention relates to a new vitamin D compound of the general formula (I) wherein: R1 a hydrogen atom or a hydroxy group; R2 is a (C1-C3)alkyl group, a hydroxy(C1-C3)alkyl group, a (C1-C2)alkoxymethyl group or a (C2-C3)alkenyl or alkynyl group; R3 is a branched or non-branched, saturated or unsaturated aliphatic 3- to 5-membered hydrocarbon or oxahydrocarbon biradical, having at least 3 atoms in the main chain and being optionally substituted with one or more substituents selected from epoxy, fluoro and hydroxy; R4 is a sec. of tert. (C3-C6)alkyl group or a (C3-C6)cycloalkyl group; and A and B are each individually hydrogen atoms or methyl groups, or A and B form together a methylene group. The invention further relates to a method of preparing these compounds and to their use in pharmacotherapy and cosmetics.
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申请公布号 |
CA2097997(A1) |
申请公布日期 |
1994.12.09 |
申请号 |
CA19932097997 |
申请日期 |
1993.06.08 |
申请人 |
DUPHAR INTERNATIONAL RESEARCH B.V. |
发明人 |
SESTELO, JOSE P.;MOURINO, ANTONIO;MASCARENAS, JOSE;HALKES, SEBASTIANUS J.;ZORGDRAGER, JAN;DIJKSTRA, GERHARDUS D.H.;VAN DE VELDE, JAN-PAUL |
分类号 |
A61K31/59;A61K8/34;A61K8/67;A61P3/02;A61Q19/00;A61Q19/08;C07C49/513;C07C401/00;(IPC1-7):C07C401/00;A61K49/00;C07D303/14;C07F7/18;A61K7/48 |
主分类号 |
A61K31/59 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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