PROCESS FOR PREPARING AND RESOLVING 2-PHENYL-3-AMINOPIPERIDINE
摘要
The present invention relates to a novel process for preparing and resolving 3-amino-2-phenylpiperidine and for synthesizing from the enantiomers of such compound certain pharmaceutically active substituted 2-phenyl-3-benzylaminopiperidines. The substituted 2-phenyl-3-benzylaminopiperidines that can be prepared by the processes of this invention are substance P receptor antagonists and are useful in the treatment and prevention of inflammatory and central nervous system disorders, as well as several other disorders.
申请公布号
WO9427966(A1)
申请公布日期
1994.12.08
申请号
WO1994IB00059
申请日期
1994.04.06
申请人
PFIZER INC.;SNYDER, WILLIAM, M.;WATSON, HARRY, A., JR.;WILCOX, GLENN, E.
发明人
SNYDER, WILLIAM, M.;WATSON, HARRY, A., JR.;WILCOX, GLENN, E.