发明名称 IN-SITU HYBRIDIZATION PROBES FOR IDENTIFICATION AND BANDING OF SPECIFIC HUMAN CHROMOSOMES AND REGIONS
摘要 The invention relates to novel primer sets useful in preparing DNA probes specific for any chromosome or part of a chromosome, particularly human chromosomes. The DNA probes so produced may be used to paint individual chromosomes or portions of chromosomes in metaphase cell spreads and in interphase nuclei. When used to paint chromosomes in metaphase spreads, R-bands are readily detectable. The method is sensitive and has been shown to paint R-bands on chromosomes pieces having as few as several hundred kilobases.
申请公布号 WO9428178(A1) 申请公布日期 1994.12.08
申请号 WO1994US06194 申请日期 1994.06.01
申请人 BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 发明人 SICILIANO, MICHAEL, J.;LIU, PU
分类号 C12N15/10;C12Q1/68 主分类号 C12N15/10
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