POST-TRANSCRIPTIONAL GENE REGULATION BY TRACE MINERALS

摘要

Methods of controlling the in vivo and in vitro expression of a heterologous protein which involve providing a cell containing a first nucleic acid encoding the heterologous polypeptide wherein at least one codon of the mRNA transcribed from the first nucleic acid has been replaced by the codon UGA operably linked to a second nucleic acid capable of directing the translation of the UGA codon as selenocysteine are described.