| 发明名称 |
TRIAMIDE-SUBSTITUTED INDOLES, BENZOFURANES AND BENZOTHIOPHENES AS INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN (MTP) AND/OR APOLIPOPROTEIN B (APO B) SECRETION |
| 摘要 |
The invention relates to triamide MTP/ApoB inhibitors of the formula 1, wherein R1-R8 are as defined in the specification, as well as pharmaceutical compositions and uses thereof, and processes for preparing the compounds. The compounds of the invention are useful for the treatment of obesity and lipid disorders.
|
| 申请公布号 |
CA2451474(C) |
申请公布日期 |
2009.06.16 |
| 申请号 |
CA20022451474 |
申请日期 |
2002.05.24 |
| 申请人 |
PFIZER PRODUCTS INC. |
发明人 |
HUATAN, HIEP;LI, JIN;MASON, CLIVE PHILIP;CHENG, HENGMIAO;BRONK, BRIAN SCOTT;BLIZE, ALAN ELWOOD;BERTINATO, PETER |
| 分类号 |
C07D209/42;A61K31/341;A61K31/343;A61K31/397;A61K31/404;A61K31/4045;A61K31/405;A61K31/4439;A61K31/4525;A61K31/4709;A61K31/501;A61K31/5377;A61P3/04;A61P3/06;A61P9/10;A61P43/00;C07D307/85;C07D401/12;C07D401/14;C07D403/12;C07D405/12;C07D409/12 |
主分类号 |
C07D209/42 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
