MONOCLONAL ANTI-IDIOTYPIC ANTI-CA125 ANTIBODIES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

摘要

Disclosed is an anti-idiotypic antibody which reacts with an anti-CA125 antibody and competes with CA125 in its binding to said anti-CA125 antibody. Furthermore, fragments of said anti-idiotypic antibody are disclosed which have essentially the same binding specificity. Additionally, the invention relates to cell lines, particularly to hybridoma 3D5 (DSM ACC2120), producing said anti-idiotypic antibodies. Also disclosed are pharmaceutical compositions containing said anti-idiotypic antibodies and specific uses of these antibodies.