The present invention provides an isolated double-stranded nucleic acid and the protein encoded by such nucleic acid that regulates hemolysis. Additionally provided is a double-stranded nucleic acid positively regulated by the positive regulator of hemolysin. Finally, methods for detecting virulent M. tuberculosis infection and for immunizing against tuberculosis are provided.
申请公布号
WO9428137(A1)
申请公布日期
1994.12.08
申请号
WO1994US05869
申请日期
1994.05.24
申请人
THE UNITED STATES OF AMERICA, AS REPRESENTED BY TH;KING, C., HAROLD;SHINNICK, THOMAS, M.;SATHISH, MUNDAYOOR
