| 摘要 |
<p>Process for the preparation of a hydroxyphenylacetic acid of formula (I) <IMAGE> where R = H, Hal, alkyl or alkoxy, and of its salts, in which the corresponding, free or salified, hydroxymandelic acid of formula (II) <IMAGE> where R has the meaning given above and M = H, K or an ammonium group, is reacted, in aqueous medium, at a temperature greater than or equal to 50@C, with formic acid in the presence of catalytic amounts of an oxygen-containing derivative of sulphur having a degree of oxidation of 2 to 4, in order to obtain the hydroxyphenylacetic acid of formula (I) which is isolated or, if desired, salified according to the usual methods, and hydroxyphenylacetic acid thus obtained.</p> |
