发明名称 WAY OF MODULATION OF INFLAMMATION AND THE IMMUNITY FUNCTION MEDIATE BY MEANS OF T-CELLS
摘要 Interleukin-10 or its analog, agonist or antagonist are use for production of pharmaceutical preparation for treating inflammation or immunity function caused by T-cells, which are followed by abnormal level of necrotic tumour factor alpha. Administered interleukin-10 or its analog according to the invention modifies the levels of interleukin-10 and interleukin-6, where the abnormal level is increased and followed by microbial infection, fever, hypotenuses, fibre necrosis, metabolic acidosis or organs dysfunction.
申请公布号 SK12994(A3) 申请公布日期 1994.12.07
申请号 SK19940000129 申请日期 1992.08.06
申请人 SCHERING CORPORATION 发明人 DE WAAL MALEFYT R.;HOWARD MAUREEN;HSU DI-HWEI;ISHIDA HIROSHI;O'GARRA ANNE;SPITS HERGEN;ZLOTNIK ALBERT
分类号 A61K38/00;A61K39/395;A61K45/00;A61P9/00;A61P9/10;A61P29/00;A61P31/04;A61P37/00;A61P37/06;A61P39/02;C07K14/05;C07K14/54;C07K16/24;(IPC1-7):A61K37/02 主分类号 A61K38/00
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