发明名称 |
Process for the production of ergoline derivatives |
摘要 |
PCT No. PCT/DE92/00088 Sec. 371 Date Oct. 7, 1992 Sec. 102(e) Date Oct. 7, 1992 PCT Filed Feb. 6, 1992 PCT Pub. No. WO92/13857 PCT Pub. Date Aug. 20, 1992.A process for the production of ergoline derivatives of general formula I is described <IMAGE> (I) in which the bonds represent two single-bonds or a double bond and a single bond. R1 means a hydrogen atom or an alkyl group with 1-6 carbon atoms R2 symbolizes a hydrogen atom or an alkyl group with 1-6 carbon atoms, R3 represents a carboxyl group or a grouping of formula -CONR4R5 or -NHCQNR6R7 with R4 and R5 meaning hydrogen or an alkyl radical with 1-6 carbons atoms optionally substituted by a hydroxy group and R6 and R7 meaning an alkyl group containing 1-4 carbon atoms and Q meaning an oxygen or sulfur atom.
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申请公布号 |
US5371000(A) |
申请公布日期 |
1994.12.06 |
申请号 |
US19920930692 |
申请日期 |
1992.10.07 |
申请人 |
SCHERING AKTIENGESELLSCHAFT |
发明人 |
HUMMEL-MAQUARDT, HEIDI;KENNECKE, MARIO;WEBER, ALFRED;NICKISCH, KLAUS;HAFFER, GREGOR |
分类号 |
A61K31/48;A61P31/04;C07D457/06;C07D457/12;C12P17/12;C12P17/18;C12R1/465;(IPC1-7):C12P17/18;C07D457/14 |
主分类号 |
A61K31/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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