PROLONGED RELEASE PHARMACEUTICAL PREPARATION, POLYMERIC COMPOSITION AS BASE FOR IT AND PROCESS FOR PREPARING THEREOF

摘要

1. A polymer for a prolonged release preparation which comprises (A) a polylactic acid and (B) a copolymer of glycolic acid and a hydroxycarboxylic acid of general formula wherein R stands for an alkyl group having 2 to 8 carbons, and wherein the weight ratio of (A) and (B) is in the range of 10/90 to 90/10. The drug is released at a constant rate from the preparation over the total release period without a large burst at the initial stage. Furthermore, the drug release period of the preparation can be freely controlled by varying the blending ratio of (A) and (B).