| 发明名称 |
2-PYRIDYLMETHYLENEPOLYAZAMACROCYCLOPHOSPHONIC ACIDS, COMPLEXES AND DERIVATIVES THEREOF, FOR USE AS CONTRAST AGENTS |
| 摘要 |
2-Pyridylmethylenepolyazamacrocyclophosphonic acid compounds and their derivatives are disclosed which may form inert complexes with Gd, Mn or Fe ions. The overall charge of the complex can be varied to alter the in vivo biolocalization. The complexes are useful as contrast agents for diagnostic purposes. |
| 申请公布号 |
WO9426275(A1) |
申请公布日期 |
1994.11.24 |
| 申请号 |
WO1994US05009 |
申请日期 |
1994.05.05 |
| 申请人 |
THE DOW CHEMICAL COMPANY |
发明人 |
KIEFER, GARRY, E.;KIM, WON, D. |
| 分类号 |
A61K49/00;A61K51/04;C07B59/00;C07D401/06;C07F5/00;C07F9/6524;C07F9/6558;C07F13/00;C07F15/02;G01R33/28;(IPC1-7):A61K31/44;A61K31/675;C07F9/30;C07F9/38;G01N24/08;C07F9/40 |
主分类号 |
A61K49/00 |
| 代理机构 |
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代理人 |
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