METHOD OF STIMULATING AND MODULATING THE IMMUNE SYSTEM OF ANIMALS WITH MICROBIAL COMPOSITIONS

摘要

The invention comprises method and compositions for stimulating the immune system of an animal by administering an apathogenic bacteria selected from the family Lactobacilliaceae in a ratio of between about 500:1 and 1:500 bacteria to macrophage, the macrophage being present in the oropharyngeal-alveolar cavity of the animal, in an acceptable carrier effective to deliver said bacteria to said oropharyngeal-alveolar cavity of the animal. The methods and compositions are particularly useful in modulating the responses of macrophages in animals to E. coli and other pathogens to reduce the risk of septic shock upon exposure to such pathogens.