| 发明名称 |
COMPOSITION OF ANTIBODIES AGAINST HEPATITIS B SURFACE ANTIGEN |
| 摘要 |
A composition comprising at least two different human monoclonal against hepatitis B surface antigen. Combination of a human monoclonal antibody which binds to a linear epitope, e.g. MAb 4-7B, and a human monoclonal antibody which binds to a conformational epitope, e.g. MAb 9H9. The composition is useful for treatment of chronic hepatitis B patients, e.g. those having received liver transplantation in order to prevent re-infection.
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| 申请公布号 |
CA2162370(A1) |
申请公布日期 |
1994.11.24 |
| 申请号 |
CA19942162370 |
申请日期 |
1994.05.09 |
| 申请人 |
STICHTING CENTRAL LABORATORIUM VAN DE BLOEDTRANSFUSIEDIENST VAN HET NEDERLANDSE RODE KRUIS |
发明人 |
ZEIJLEMAKER, WILLEM PIETER;STRICKER, ELISABETH ANTONIA MARIA;ENGELBERTUS, JOZEF MARIA |
| 分类号 |
C12N15/09;A61K38/00;A61K39/29;A61K39/395;A61K39/42;A61P31/12;C07K16/08;C12P21/08;C12R1/91;(IPC1-7):A61K39/42;C12N15/13 |
主分类号 |
C12N15/09 |
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