COMPOSITION OF ANTIBODIES AGAINST HEPATITIS B SURFACE ANTIGEN
摘要
A composition comprising at least two different human monoclonal antibodies against hepatitis B surface antigen. Combination of a human monoclonal antibody which binds to a linear epitope, e.g. MAb 4-7B, and a human monoclonal antibody which binds to a conformational epitope, e.g. MAb 9H9. The composition is useful for treatment of chronic hepatitis B patients, e.g. those having received liver transplantation in order to prevent re-infection.
申请公布号
WO9426784(A1)
申请公布日期
1994.11.24
申请号
WO1994NL00102
申请日期
1994.05.09
申请人
STICHTING CENTRAAL LABORATORIUM VAN DE BLOEDTRANSF;ZEIJLEMAKER, WILLEM, PIETER;STRICKER, ELISABETH, ANTONIA, MARIA;AL, ENGELBERTUS, JOZEF, MARIA
发明人
ZEIJLEMAKER, WILLEM, PIETER;STRICKER, ELISABETH, ANTONIA, MARIA;AL, ENGELBERTUS, JOZEF, MARIA