发明名称 COMPOSITION OF ANTIBODIES AGAINST HEPATITIS B SURFACE ANTIGEN
摘要 A composition comprising at least two different human monoclonal antibodies against hepatitis B surface antigen. Combination of a human monoclonal antibody which binds to a linear epitope, e.g. MAb 4-7B, and a human monoclonal antibody which binds to a conformational epitope, e.g. MAb 9H9. The composition is useful for treatment of chronic hepatitis B patients, e.g. those having received liver transplantation in order to prevent re-infection.
申请公布号 WO9426784(A1) 申请公布日期 1994.11.24
申请号 WO1994NL00102 申请日期 1994.05.09
申请人 STICHTING CENTRAAL LABORATORIUM VAN DE BLOEDTRANSF;ZEIJLEMAKER, WILLEM, PIETER;STRICKER, ELISABETH, ANTONIA, MARIA;AL, ENGELBERTUS, JOZEF, MARIA 发明人 ZEIJLEMAKER, WILLEM, PIETER;STRICKER, ELISABETH, ANTONIA, MARIA;AL, ENGELBERTUS, JOZEF, MARIA
分类号 C12N15/09;A61K38/00;A61K39/29;A61K39/395;A61K39/42;A61P31/12;C07K16/08;C12P21/08;C12R1/91 主分类号 C12N15/09
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