发明名称 |
alpha -1-antichymotrypsin, analogues and methods of production |
摘要 |
The invention provides alpha -1-antichymotrypsin and protein preparations comprising human alpha -1-antichymotrypsin produced by E. coli cells transformed with a DNA sequence encoding human alpha -1-antichymotrypsin. The invention also provides methods for producing alpha -1-antichymotrypsin. The invention further provides analogues of alpha -1-antichymotrypsin that exhibit antichymotrypsin, anti-trypsin and anti-thrombin activity and methods of producing the analogues.
|
申请公布号 |
US5367064(A) |
申请公布日期 |
1994.11.22 |
申请号 |
US19930005908 |
申请日期 |
1993.01.15 |
申请人 |
THE TRUSTEES OF THE UNIVERSITY OF PENNYLSVANIA |
发明人 |
RUBIN, HARVEY;WANG, ZHI M.;COOPERMAN, BARRY S.;SCHECHTER, NORMAN |
分类号 |
A61K38/00;C07K14/81;(IPC1-7):C07H21/04;C07K13/00;C12N15/22 |
主分类号 |
A61K38/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|