发明名称 |
Peptide production |
摘要 |
A method of producing a substance comprising a peptide, involves incorporating a DNA sequence coding for the peptide into a gene of a mammal (such as a sheep) coding for a milk whey protein in such a way that the DNA sequence is expressed in the mammary gland of the adult female mammal. The substance may be an (optionally modified) protein such as a blood coagulation factor. The DNA sequence is preferably inserted into the first exon of a gene coding for a whey protein such as beta-lactoglobulin. The substance will generally be recovered from milk of the female mammal, but may (for example if it is an enzyme) be used in situ.
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申请公布号 |
US5366894(A) |
申请公布日期 |
1994.11.22 |
申请号 |
US19910796439 |
申请日期 |
1991.11.22 |
申请人 |
PHARMACEUTICAL PROTEINS LIMITED |
发明人 |
CLARK, ANTHONY J.;LATHE, RICHARD |
分类号 |
A01K67/027;C12N15/85;C12N15/89;(IPC1-7):C12N15/00;C12N5/00 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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