发明名称 |
Human chondromodulin-I protein. |
摘要 |
A novel human chondromodulin-I protein having a molecular weight of about 26,000 dalton on SDS-PAGE and capable of stimulating the growth of chondrocytes with or without FGF, promoting the differential potency of said cells, and inhibiting the growth of vascular endothelial cells, a DNA encoding said protein, expression vector containing said DNA, a transformant capable of producing recombinant chondromodulin-I protein, a process for producing chondromodulin-I protein by culturing said transformant and a pharmaceutical composition containing chondromodulin-I protein as an active ingredient. |
申请公布号 |
EP0624645(A1) |
申请公布日期 |
1994.11.17 |
申请号 |
EP19940107364 |
申请日期 |
1994.05.11 |
申请人 |
MITSUBISHI KASEI CORPORATION |
发明人 |
SUZUKI, FUJIO;HIRAKI, YUJI;TAKAHASHI, KAZUHIRO;SUZUKI, JUNKO;KONDO, JUN;KOHARA, ATSUKO;MORI, AKIKO;YAMADA, EI |
分类号 |
C12N15/09;C12N15/16;A61K38/00;A61P35/00;A61P43/00;C07K14/47;C07K14/51;C12N5/10;C12P21/02 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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