| 发明名称 |
BIOLOGICALLY ACTIVE HUMAN IL-1 PROTEIN |
| 摘要 |
<p>Recombinant DNA cloning vehicle contg. the human interleukin-1 (IL-1) gene sequence is new. In partic., the vehicle contains the sequence coding for a new specified 287 amino acid sequence or novel fragments of it. Also claimed are (1) a pure cDNA of 1507bp (and its 1-606; 1-677; 1355-1507; 482-1501; 482-677 and 1355-1507 fragments); (2) microorganisms or mammalian tissue cells contg. these DNA sequences and (3) antibodies to human IL-1 raised using the new aminoacids as immunogens.</p> |
| 申请公布号 |
JPH06315393(A) |
申请公布日期 |
1994.11.15 |
| 申请号 |
JP19930288777 |
申请日期 |
1993.10.26 |
| 申请人 |
MASSACHUSETTS INST OF TECHNOL <MIT>;NEW INGURANDO MEDICAL CENTER HOSUPITARUZU INC;TRUSTEES OF TAFUTSU KARETSUJI:THE;UERESUREI KARETSUJI |
发明人 |
FUIRITSUPU II AURON;CHIYAARUSU EE DEINARERO;ANDORIYUU SHII UEBU;AREKISANDAA RITSUCHI;SHIERUDON EMU UORUFU;RII GEERUKE;RANII JIEE ROOZENWATSUSAA |
| 分类号 |
A61K38/00;A61K39/395;C07K14/545;C12N1/00;C12N1/21;C12N5/00;C12N5/10;C12N15/00;C12N15/09;C12N15/25;C12P21/02;C12R1/19;(IPC1-7):C12P21/02 |
主分类号 |
A61K38/00 |
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