发明名称 Substituted benzoylbenzene-, biphenyl- and 2-oxazole- alkanoic acid compounds
摘要 There are disclosed substituted benzoylbenzene-, biphenyl- and 2-oxazole- alkanoic acid derivatives and the pharmacologically acceptable salts thereof as inhibitors of PLA2 and lipoxygenase, and their use in the treatment of inflammatory conditions, such as rheumatoid arthritis, ulcerative colitis, psoriasis and other immediate hypersensitivity reactions; in the treatment of leukotriene-mediated naso-bronchial obstructive air-passageway conditions, such as allergic rhinitis, allergic bronchial asthma and the like; and as gastric cytoprotective agents.
申请公布号 US5364944(A) 申请公布日期 1994.11.15
申请号 US19930001141 申请日期 1993.01.06
申请人 AMERICAN HOME PRODUCTS CORPORATION 发明人 FAILLI, AMEDEO A.;KREFT, III, ANTHONY F.;MUSSER, JOHN H.;BANKER, ANNETTE L.;NELSON, JAMES A.;SHAH, URESH S.;KUBRAK, DENNIS M.
分类号 C07C45/00;C07C45/63;C07C45/72;C07C59/90;C07C69/738;C07C205/45;C07C255/40;C07D215/14;C07D263/32;C07D277/24;C07D413/12;(IPC1-7):C07D233/54 主分类号 C07C45/00
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