摘要 |
<p>A biosensor substrate is described which comprises: (a) a body (2) having side walls (9) and a solid floor (10) defining a chamber (8) to hold a first solution; (b) at least one open aperture in the solid floor to allow for the structural integrity of a bilayer lipid membrane (5) containing an analyte receptor (e.g., an ion channel receptor) (6) across the aperture; and (c) a chamber (3) below the solid floor for a second solution in contact with the membrane containing the receptor.</p> |