DOWNREGULATION OF ALLERGEN-SPECIFIC IMMUNE RESPONSE
摘要
Synthetic peptides are provided for effecting immunotherapy. The peptides have an amino acid sequence comprising at least a portion of the CDR3 region of a T-cell receptor and capable of eliciting a T-cell response, particularly an amino acid sequence encoded by a nucleotide sequence comprising the J-gene of the alpha -chain and/or beta -chain of the TCR. The peptides are particularly useful in suppressing an immune response to an antigen, particularly an allergenic antigen.
申请公布号
WO9425489(A1)
申请公布日期
1994.11.10
申请号
WO1994CA00228
申请日期
1994.04.26
申请人
UNIVERSITY OF MANITOBA;MOHAPATRA, SHYAM, S.;SEHON, ALEC, H.