3-HALO-3-HETARYLCARBOXYLIC ACID DERIVATIVES, AND PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION

摘要

The invention concerns 3-halo-3-heteroaryl carboxylic acid derivatives of formula (1) in which R is a formyl group, a CO2H group or a group which can be hydrolysed to give a COOH group and the other substituents are as follows: R2 and R3 are halogen, C1-C4 alkyl, C1-C4 haloalkyl, C1-C4 alkoxy, C1-C4 haloalkoxy or C1-C4 alkylthio; X is nitrogen or CR13, R13 being hydrogen or forming, together with R3, an alkylene or alkenylene chain in which each methylene group may be replaced by oxygen: R4 is an optionally substituted five-membered or six-membered heteroaromatic ring containing one to the nitrogen atoms and/or a sulphur or oxygen atom: R5 is hydrogen or optionally substituted alkyl, alkenyl, alkinyl, cycloalkyl or phenyl: Y is sulphur, oxygen or a single bond: Z is halogen.