| 发明名称 |
CYCLOOXYGENASE AND 5-LIPOXYGENASE INHIBITING N(3-BIPHENYLYL- 1(S)-METHYL-2-PROPENYL) ACETOHYDROXAMIC ACID DERIVATIVES |
| 摘要 |
The present invention is concerned with novel hydroxamic acid derivatives of formula (I) and their use in medical therapy, particularly in the prophylaxis or treatment of clinical conditions for which an inhibitor of the lipoxygenase or cyclooxygenase mediated arachidonic acid metabolic pathway is indicated. The invention also relates to pharmaceutical formulations and processes for the preparation of compounds according to the invention. In formula (I), X is cyano, fluoro, or chloro; or a salt, solvate, or physiologically functional derivative thereof.
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| 申请公布号 |
CA2161544(A1) |
申请公布日期 |
1994.11.10 |
| 申请号 |
CA19942161544 |
申请日期 |
1994.04.26 |
| 申请人 |
WELLCOME FOUNDATION LIMITED (THE) |
发明人 |
HODGSON, SIMON TEANBY;WATES, PETER JOHN |
| 分类号 |
A61K31/165;A61K31/275;A61P1/00;A61P1/04;A61P11/00;A61P43/00;C07C17/263;C07C33/28;C07C33/48;C07C45/00;C07C45/72;C07C49/235;C07C239/10;C07C239/18;C07C255/53;C07C255/56;C07C255/60;C07C259/06;C07C271/00;C07C271/08;C07C275/64;(IPC1-7):C07C259/06;C07D309/12;C07C271/14;A61K31/16;C07C239/22;C07C255/49;C07C255/64 |
主分类号 |
A61K31/165 |
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