| 摘要 |
The invention provides methods and compositions for the treatment and/or prevention or a variety of disease conditions. The methods involve the administration of an effective amount of a therapeutic catalyst to a patient. A therapeutic catalyst is an enzyme, or other catalyst, capable of catalyzing a chemical reaction employing a carbohydrate or a carbohydrate portion of a glycoconjugate as a substrate. Therapeutic catalysts are selected so as to catalyze reaction that results in the structural alteration of at least one member of a receptor binding pair of molecules, whereby the interaction between receptor binding pair members is disrupted. The invention also provides compositions containing therapeutic catalysts for use in the subject methods. Diseases that may be treated by therapeutic catalysts include infections diseases, cancer, and autoimmune diseases. |
