摘要 |
<p>Antigenic conjugate of the formula (SPNE)n - (OMPC> wherein SPNE is a selected principal neutralisation epitope of HIV (as defined in Table A), or a fragment thereof of at least five amino acids; OMPC is the purified outer membrane proteosome of Neisseria, preferably N.meningitidis; n is from 1 to 200; may be used in vaccines. The conjugate may be substituted by anion(s), and conjugation may be via a biogeneric spacer.</p> |